High-resolution structure analysis and directed mutagenesis experiments may at last be brought into step by the use of functional group analogues that alter individual atoms
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Sigler, P. Chemogenetics. Nat Struct Mol Biol 1, 3–4 (1994). https://doi.org/10.1038/nsb0194-3
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DOI: https://doi.org/10.1038/nsb0194-3