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Predicting stone episodes using cystine capacity

Cystine capacity is an assay for assessing urinary cystine saturation and risk of a stone episode in patients with cystinuria. Lowering the threshold for this test improves its sensitivity, potentially enabling relaxation of follow-up regimens for patients at lowest risk of stone episodes and dose modification of medications for those at highest risk.

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Figure 1: Distribution of cystine capacity measurements in a recent study of 48 patients with cystinuria.


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Correspondence to Matthew Bultitude or Kay Thomas.

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The authors declare no competing financial interests.

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Bultitude, M., Thomas, K. Predicting stone episodes using cystine capacity. Nat Rev Urol 15, 8–9 (2018).

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