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Integrating genomics to dig deeper into Wilms tumour biology

A new study provides a comprehensive catalogue of the genetic changes in Wilms tumour. Understanding the interplay between genetic and epigenetic aberrations during tumorigenesis and clonal evolution is fundamental to enabling prediction of who is at risk and which tumours will relapse when so many are curable.

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Correspondence to Kathy Pritchard-Jones.

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Mifsud, W., Pritchard-Jones, K. Integrating genomics to dig deeper into Wilms tumour biology. Nat Rev Urol 14, 703–704 (2017).

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