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Paediatrics

New cryptorchidism guidelines reach a consensus

The American Urological Association has released a new guideline on the evaluation and treatment of cryptorchidism, recommending early orchiopexy as the first-line treatment for both the congenital and acquired forms of the disease; hormonal therapy is not recommended. Given similarities with current European recommendations, transatlantic consensus has been achieved.

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References

  1. Bay, K., Main, K. M., Toppari, J. & Skakkebæk, N. E. Testicular descent: INSL3, testosterone, genes and the intrauterine milieu. Nat. Rev. Urol. 8, 187–196 (2011).

    Article  CAS  Google Scholar 

  2. Kolon, T. F. et al. Evaluation and treatment of cryptorchidism: AUA guideline. J. Urol. 192, 337–345 (2014).

    Article  Google Scholar 

  3. Tekgül, S. et al. Guidelines on Pediatric Urology. European Association of Urology [online], (2014).

    Google Scholar 

  4. Ritzén, E. M. et al. Nordic consensus on treatment of undescended testes. Acta Paediatr. 96, 638–643 (2007).

    Article  Google Scholar 

  5. Gapany, C. et al. Management of cryptorchidism in children: guidelines. Swiss Med. Wkly 138, 492–498 (2008).

    PubMed  Google Scholar 

  6. van der Plas, E. M. et al. Long-term testicular volume after orchiopexy at diagnosis of acquired undescended testis. J. Urol. 190, 257–262 (2013).

    Article  Google Scholar 

  7. Kollin, C., Hesser, U., Ritzén, E. M. & Karpe, B. Testicular growth from birth to two years of age, and the effect of orchidopexy at age nine months: a randomized, controlled study. Acta Paediatr. 95, 318–324 (2006).

    Article  Google Scholar 

  8. Cortes, D., Thorup, J. & Visfeldt, J. Hormonal treatment may harm the germ cells in 1 to 3-year-old boys with cryptorchidism. J. Urol. 163, 1290–1292 (2000).

    Article  CAS  Google Scholar 

  9. Schwentner, C. et al. Neoadjuvant gonadotropin-releasing hormone therapy before surgery may improve the fertility index in undescended testes: a prospective randomized trial. J. Urol. 173, 974–977 (2005).

    Article  CAS  Google Scholar 

  10. Toppari, J., Virtanen, H. E., Main, K. M. & Skakkebæk, N. E. Cryptorchidism and hypospadias as a sign of testicular dysgenesis syndrome (TDS): environmental connection. Birth Defects Res. A Clin. Mol. Teratol. 88, 910–919 (2010).

    Article  CAS  Google Scholar 

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Correspondence to Jorma Toppari.

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Toppari, J. New cryptorchidism guidelines reach a consensus. Nat Rev Urol 11, 432–433 (2014). https://doi.org/10.1038/nrurol.2014.180

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