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Bladder cancer

Tumour recurrence after radical nephroureterectomy for UTUC

Nature Reviews Urology volume 11, pages 15–16 (2014)Cite this article

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Bladder cancer recurrence after radical nephroureterectomy for upper tract urothelial carcinoma (UTUC) is a common occurrence. A new nomogram, based on retrospective analysis of a large multicentre cohort, has been shown to predict the risk of intravesical recurrence. Despite limitations, this model could help clinicians to provide personalized postoperative management.

A characteristic feature of urinary tract tumours is the involvement of multiple anatomical locations in the urinary tract.1 Approximately 8–13% of patients with upper tract urothelial carcinoma (UTUC) have synchronous bladder cancer; intravesical recurrence occurs in up to 50% of these patients during follow-up assessment after radical nephroureterectomy (RNU), requiring cystoscopic evaluation.2,3 Single postoperative administration of 40 mg of intravesical mitomycin C (MMC) has been shown to reduce the risk of intravesical recurrence by 11% within the first year following RNU.4

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References

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Affiliations

  1. Department of Urology, Hôpital Claude Huriez, CHRU Lille, Université Lille Nord de France, rue Michel Polonovski, Lille, 59000, France

    Adil Ouzzane

  2. Department of Urology, Hôpital Privé de la Louvière, Générale de Santé, 20 rue de la Louvière, Lille, 59000, France

    Pierre Colin

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  1. Adil Ouzzane
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  2. Pierre Colin
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Correspondence to Pierre Colin.

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The authors declare no competing financial interests.

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Ouzzane, A., Colin, P. Tumour recurrence after radical nephroureterectomy for UTUC. Nat Rev Urol 11, 15–16 (2014). https://doi.org/10.1038/nrurol.2013.299

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  • DOI: https://doi.org/10.1038/nrurol.2013.299

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