Bladder cancer risk assessment is currently based on an individual's age and history of exposure to known carcinogens. A new report illustrates how interactions between cigarette smoking and germline genetic variation can identify those at particularly high risk, who could be targeted in future bladder cancer prevention and screening efforts.
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Furberg, H., Bochner, B. Towards risk stratification in bladder cancer. Nat Rev Urol 10, 374–375 (2013). https://doi.org/10.1038/nrurol.2013.114
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DOI: https://doi.org/10.1038/nrurol.2013.114