More effective treatment strategies are desperately needed for non-muscle-invasive bladder cancer due to the high costs of therapy and surveillance, and the substantial risk of ongoing recurrence or progression to muscle-invasive disease. A recent paper reviews the state of the art regarding combination intravesical chemotherapy and hyperthermia for bladder cancer.
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References
Hall, M. C. et al. Guideline for the management of nonmuscle invasive bladder cancer (stages Ta, T1, and Tis): 2007 update. J. Urol. 178, 2314–2330 (2007).
Lammars, R. J. et al. The role of a combined regimen with intravesical chemotherapy and hyperthermia in the management of non-muscle-invasive bladder cancer: a systematic review. Eur. Urol. 60, 81–93 (2011).
Colombo, R., Salonia, A. S., Leib, Z., Pavone-Macaluso, M. & Engelstein, D. Long-term outcomes of a randomized controlled trial comparing thermochemotherapy with mitomycin-C alone as adjuvant treatment for non-muscle-invasive bladder cancer. Brit. J. Urol. 107, 912–918 (2010).
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Gingrich, J. Chemohyperthermia for bladder cancer—clinically effective?. Nat Rev Urol 8, 414–416 (2011). https://doi.org/10.1038/nrurol.2011.104
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DOI: https://doi.org/10.1038/nrurol.2011.104
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