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Bladder cancer

Restaging TUR reduces recurrence and progression risk

Transurethral resection (TUR) is widely used to manage early-stage bladder cancer. A recent study has confirmed that a second, or restaging, TUR is associated with a lower risk of progression and cancer-related death. Restaging TUR is therefore recommended as a standard of care in patients with stage T1 bladder cancer.

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Figure 1: Recurrence-free survival.

References

  1. Divrik, R. T., Sahin, A. F., Yildirim, U., Altok, M. & Zorlu, F. Impact of routine second transurethral resection on the long-term outcome of patients with newly diagnosed pT1 urothelial carcinoma with respect to recurrence, progression rate, and disease-specific survival: a prospective randomised clinical trial. Eur. Urol. 58, 185–190 (2010).

    Article  PubMed  Google Scholar 

  2. Kulkarni, G. S. et al. An updated critical analysis of the treatment strategy for newly diagnosed high-grade T1 (previously T1G3) bladder cancer. Eur. Urol. 57, 60–70 (2009).

    Article  PubMed  Google Scholar 

  3. Hall, M. C. et al. Guideline for the management of nonmuscle invasive bladder cancer (stages Ta, T1, and Tis): 2007 update. J. Urol. 178, 2314–2330 (2007).

    Article  PubMed  Google Scholar 

  4. Babjuk, M. et al. EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder. Eur. Urol. 54, 303–314 (2008).

    Article  PubMed  Google Scholar 

  5. Brausi, M. et al. Variability in the recurrence rate at first follow-up cystoscopy after TUR in stage Ta T1 transitional cell carcinoma of the bladder: a combined analysis of seven EORTC studies. Eur. Urol. 41, 523–531 (2002).

    Article  PubMed  Google Scholar 

  6. Dutta, S. C. et al. Clinical under staging of high risk nonmuscle invasive urothelial carcinoma treated with radical cystectomy. J. Urol. 166, 490–493 (2001).

    Article  CAS  PubMed  Google Scholar 

  7. Herr, H. W., Donat, S. M. & Dalbagni, G. Can restaging transurethral resection of T1 bladder cancer select patients for immediate cystectomy? J. Urol. 177, 75–79 (2007).

    Article  PubMed  Google Scholar 

  8. Herr, H. W. Restaging transurethral resection of high risk superficial bladder cancer improves the initial response to bacillus Calmette-Guerin therapy. J. Urol. 174, 2134–2137 (2005).

    Article  PubMed  Google Scholar 

  9. Grimm, M. O. et al. Effect of routine repeat transurethral resection for superficial bladder cancer: a long-term observational study. J. Urol. 170, 433–437 (2003).

    Article  PubMed  Google Scholar 

  10. Divrik, R. T., Yildirim, U., Zorlu, F. & Ozen, H. The effect of repeat transurethral resection on recurrence and progression rates in patients with T1 tumors of the bladder who received intravesical mitomycin: a prospective, randomized clinical trial. J. Urol. 175, 1641–1644 (2006).

    Article  CAS  PubMed  Google Scholar 

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Dalbagni, G. Restaging TUR reduces recurrence and progression risk. Nat Rev Urol 7, 649–650 (2010). https://doi.org/10.1038/nrurol.2010.189

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