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Osteoarthritis

Bisphosphonates and OA — is there a bone and joint connection?

Nature Reviews Rheumatology volume 14, pages 185–186 (2018)Cite this article

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Bisphosphonates have been proposed as a potential disease-modifying treatment for osteoarthritis (OA); however, it is as yet unclear if this treatment is effective. Evidence from a new meta-analysis raises the question of whether bisphosphonates can reduce damage in OA.

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Figure 1: Key elements of osteoarthritis pathology.

References

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Acknowledgements

The work of N.E.L. is supported in part by NIH grant P50 AR063043 and the endowment for geriatrics and rheumatology at UC Davis.

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Authors and Affiliations

  1. Department of Medicine, Center for Musculoskeletal Health, University of California at Davis School of Medicine, Sacramento, CA, USA

    Nancy E. Lane

  2. Department of Epidemiology, University of California at San Francisco, San Francisco, CA, USA

    Nancy E. Lane

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  1. Nancy E. Lane
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Correspondence to Nancy E. Lane.

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The author declares no competing financial interests.

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Lane, N. Bisphosphonates and OA — is there a bone and joint connection?. Nat Rev Rheumatol 14, 185–186 (2018). https://doi.org/10.1038/nrrheum.2018.18

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