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Osteoarthritis

Inflammation and fibrosis in adipose tissue of osteoarthritic joints

The infrapatellar fat pad and other adipose tissues in close proximity to the joint have been linked with osteoarthritis (OA), but the nature of this relationship is unclear. Two new studies elucidate the features of intra-articular adipose tissues in OA and raise important questions for future investigations.

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Acknowledgements

The authors' work is supported by the Dutch Arthritis Foundation (LLP24; A.I.-F., M.K.) and the Innovative Medicine Initiative Joint Undertaking funded project Be The Cure (115142–2; A.I.-F.).

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Correspondence to Margreet Kloppenburg.

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The authors declare no competing financial interests.

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Ioan-Facsinay, A., Kloppenburg, M. Inflammation and fibrosis in adipose tissue of osteoarthritic joints. Nat Rev Rheumatol 13, 325–326 (2017). https://doi.org/10.1038/nrrheum.2017.53

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