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TNF inhibitors and structural damage in ankylosing spondylitis

Nature Reviews Rheumatology volume 14, pages 56 (2018) | Download Citation

Whether TNF inhibitors prevent structural damage in ankylosing spondylitis remains a controversial topic, as three prospective trials failed to show any evidence to support this notion. However, data are accumulating from retrospective analyses of well-characterized cohorts of patients that could provide the solution to this controversy.

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  1. Division of Arthritis and Rheumatic Diseases, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, USA.

    • Atul Deodhar


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Competing interests

A.D. declares that he has acted on the advisory board for or received research grants from Abbvie, Eli Lilly, Janssen, Novartis, Pfizer and UCB.

Corresponding author

Correspondence to Atul Deodhar.

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