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Intra-articular steroids for TMJ arthritis—caution needed

Nature Reviews Rheumatology volume 11, pages 566–567 (2015)Cite this article

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In the past decade, the consequences of temporomandibular joint arthritis in patients with juvenile idiopathic arthritis have received increasing attention. Intra-articular corticosteroid injections have been suggested as a treatment option, but concerns that this treatment could reduce mandibular growth have been raised and are supported by new data published in The Journal of Rheumatology.

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References

  1. Kuseler, A., Pedersen, T. K., Gelineck, J. & Herlin, T. A 2 year followup study of enhanced magnetic resonance imaging and clinical examination of the temporomandibular joint in children with juvenile idiopathic arthritis. J. Rheumatol. 32, 162–169 (2005).

    PubMed  Google Scholar 

  2. Twilt, M., Mobers, S. M., Arends, L. R., ten Cate, R. & van Suijlekom-Smit, L. Temporomandibular involvement in juvenile idiopathic arthritis. J. Rheumatol. 31, 1418–1422 (2004).

    PubMed  Google Scholar 

  3. von Bremen, J. & Ruf, S. Juvenile idiopathic arthritis—and now? A systematic literature review of changes in craniofacial morphology. J. Orofac. Orthop. 73, 265–276 (2012).

    Article  Google Scholar 

  4. Stoustrup, P. et al. Intra-articular steroid injection for temporomandibular joint arthritis in juvenile idiopathic arthritis: a systematic review on efficacy and safety. Semin. Arthritis Rheum. 43, 63–70 (2013).

    Article  CAS  Google Scholar 

  5. Lochbühler, N., Saurenmann, R., Müller, L. & Kellenberger, C. Magnetic resonance imaging assessment of temporomandibular joint involvement and mandibular growth following corticosteroid injection in juvenile idiopathic arthritis. J. Rheumatol. http://dx.doi.org/10.3899/jrheum.141502.

  6. Stoustrup, P. et al. Reduced mandibular growth in experimental arthritis in the temporomandibular joint treated with intra-articular corticosteroid. Eur. J. Orthod. 30, 111–119 (2008).

    Article  Google Scholar 

  7. Ringold, S., Thapa, M., Shaw, E. A. & Wallace, C. A. Heterotopic ossification of the temporomandibular joint in juvenile idiopathic arthritis. J. Rheumatol. 38, 1423–1428 (2011).

    Article  Google Scholar 

  8. Enlow, D. H. & Hans, M. G. in Essentials of Facial Growth 57–78 (Saunders, 1996).

    Google Scholar 

  9. Arabshahi, B. & Cron, R. Q. Temporomandibular joint arthritis in juvenile idiopathic arthritis: the forgotten joint. Curr. Opin. Rheumatol. 18, 490–495 (2006).

    Article  Google Scholar 

  10. Øgaard, B. (ed.). Semin. Orthod. 21, 71–148 (2015).

    Article  Google Scholar 

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Authors and Affiliations

  1. Aarhus University Hospital, Section of Orthodontics, Vennelyst Boulevard 9-11, Aarhus, 8000, Denmark

    Peter Stoustrup

  2. Department of Pediatrics, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, Aarhus, 8200, Denmark

    Marinka Twilt

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  1. Peter Stoustrup
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  2. Marinka Twilt
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Correspondence to Marinka Twilt.

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Stoustrup, P., Twilt, M. Intra-articular steroids for TMJ arthritis—caution needed. Nat Rev Rheumatol 11, 566–567 (2015). https://doi.org/10.1038/nrrheum.2015.97

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