The new ACR guideline for the treatment of rheumatoid arthritis (RA) is technically solid, but the new recommendations miss some of the most topical issues in RA therapeutics. The fact that evidence from many high-quality clinical studies in RA was not deemed sufficient to support stronger recommendations is also worrying.
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The author has received support and grants for research from AbbVie, Amgen, Bristol-Myers Squibb, GlaxoSmithKline, Pfizer, Roche and UCB, and has received consultancy honoraria from AbbVie, Biotest, Bristol-Myers Squibb, Celgene, Crescendo, GlaxoSmithKline, Janssen, Lilly, Merck, Novartis, Pfizer, Roche, UCB and Vertex.
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van Vollenhoven, R. Missed opportunities in the 2015 ACR guideline for RA treatment. Nat Rev Rheumatol 12, 135–136 (2016). https://doi.org/10.1038/nrrheum.2015.181