Gene variants have been discovered that cause a range of vascular inflammatory phenotypes with a characteristic onset in childhood. What might these exciting findings mean for the understanding, diagnosis and treatment of systemic vasculitis?
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Acknowledgements
The authors are supported by Instituto de Salud Carlos III (PIE13/00033) and Ministerio de Economía y Competitividad (SAF11/30073).
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M.C.C. has acted as a consultant for GSK. J.I.A. declares no competing interests.
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Cid, M., Aróstegui, J. New insights into the molecular basis of systemic vasculitis. Nat Rev Rheumatol 10, 323–324 (2014). https://doi.org/10.1038/nrrheum.2014.75
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DOI: https://doi.org/10.1038/nrrheum.2014.75