Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Paediatric rheumatology

A disease activity index for juvenile SpA—a welcome addition

A lack of universally accepted classification criteria for patients with juvenile spondyloarthritis (SpA) has hindered efforts to develop tools to assess the severity and progression of this disease. With the publication of a new juvenile SpA disease activity index, has this gap now been bridged, and is it a comprehensive tool for the clinic?

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Weiss, P. F. et al. Development and retrospective validation of the juvenile spondyloarthritis disease activity (JSpADA) index. Arthritis Care Res. (Hoboken) http://dx.doi.org/10.1002/acr.22411.

  2. Petty, R. E. et al. International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001. J. Rheumatol. 31, 390–392 (2004).

    Google Scholar 

  3. Beukelman, T. et al. 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: initiation and safety monitoring of therapeutic agents for the treatment of arthritis and systemic features. Arthritis Care Res. (Hoboken) 63, 465–482 (2011).

    Article  Google Scholar 

  4. Wallace, C. A. et al. American College of Rheumatology provisional criteria for defining clinical inactive disease in select categories of juvenile idiopathic arthritis. Arthritis Care Res. (Hoboken) 63, 929–936 (2011).

    Article  Google Scholar 

  5. Horneff, G. et al. Efficacy and safety of open-label etanercept on extended oligoarticular juvenile idiopathic arthritis, enthesitis-related arthritis and psoriatic arthritis: part 1 (week 12) of the CLIPPER study. Ann. Rheum. Dis. 73, 1114–1122 (2013).

    Article  Google Scholar 

  6. Rachlis, A. C. et al. Validation of BASDAI and BASFI in children with spondyloarthritis [abstract 24]. Arthritis Rheum. 66 (Suppl. 11), S38 (2014).

    Article  Google Scholar 

  7. Batthish, M. et al. Intra-rater reliability of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and the Bath Ankylosing Spondylitis Functional Index (BASFI) in children with spondyloarthritis [abstract]. Arthritis Rheum. 62 (Suppl. 10), S225 (2010).

    Google Scholar 

  8. Stoll, M. L., Bhore, R., Dempsey-Robertson, M. & Punaro, M. Spondyloarthritis in a pediatric population: risk factors for sacroiliitis. J. Rheumatol. 37, 2402–2408 (2010).

    Article  Google Scholar 

  9. Filocamo, G. et al. A new approach to clinical care of juvenile idiopathic arthritis: the Juvenile Arthritis Multidimensional Assessment Report. J. Rheumatol. 38, 938–953 (2011).

    Article  Google Scholar 

  10. Weiss, P. F., Beukelman, T., Schanberg, L. E., Kimura, Y. & Colbert, R. A. Enthesitis-related arthritis is associated with higher pain intensity and poorer health status in comparison with other categories of juvenile idiopathic arthritis: the Childhood Arthritis and Rheumatology Research Alliance Registry. J. Rheumatol. 39, 2341–2351 (2012).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Roberta A. Berard.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Berard, R., Laxer, R. A disease activity index for juvenile SpA—a welcome addition. Nat Rev Rheumatol 10, 642–644 (2014). https://doi.org/10.1038/nrrheum.2014.150

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrrheum.2014.150

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing