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Connective tissue diseases

SLE-associated arthropathy: truly a benign entity?

Nature Reviews Rheumatology volume 8, pages 695–696 (2012)Cite this article

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Arthropathy is a common manifestation of systemic lupus erythematosus (SLE), but remains poorly understood. Recent ultrasonographic evidence demonstrating high levels of joint and tendon pathology in SLE challenges our previous concepts of arthritis subtypes in this multisystem disease.

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Figure 1: Strategy outline for the investigation of a patient with SLE and suspected musculoskeletal involvement.

References

  1. Petri, M. Treatment of systemic lupus erythematosus: an update. Am. Fam. Physician 57, 2753–2760 (1998).

    CAS  PubMed  Google Scholar 

  2. van Vugt, R. M., Derksen, R. H., Kater, L. & Bijlsma, J. W. Deforming arthropathy or lupus and rhupus hands in systemic lupus erythematosus. Ann. Rheum. Dis. 57, 540–544 (1998).

    Article  CAS  Google Scholar 

  3. SáRibeiro, D. et al. Magnetic resonance imaging of Jaccoud's arthropathy in systemic lupus erythematosus. Joint Bone Spine 77, 241–245 (2010).

    Article  Google Scholar 

  4. Ostendorf, B., Scherer, A., Specker, C., Mödder, U. & Schneider, M. Jaccoud's arthropathy in systemic lupus erythematosus: differentiation of deforming and erosive patterns by magnetic resonance imaging. Arthritis Rheum. 1, 157–165 (2003).

    Article  Google Scholar 

  5. Gabba, A. et al. Joint and tendon involvement in systemic lupus erythematosus: an ultrasound study of hands and wrists in 108 patients. Rheumatology (Oxford) http://dx.doi.org/10.1093/rheumatology/kes226.

  6. Szkudlarek, M. et al. Ultrasonography of the metacarpophalangeal and proximal interphalangeal joints in rheumatoid arthritis: a comparison with magnetic resonance imaging, conventional radiography and clinical examination. Arthritis Res. Ther. 8, R52 (2006).

    Article  Google Scholar 

  7. Iagnocco, A. et al. Wrist joint involvement in systemic lupus erythematosus. An ultrasonographic study. Clin. Exp. Rheumatol. 22, 621–624 (2004).

    CAS  PubMed  Google Scholar 

  8. Delle Sedie, A. et al. Ultrasound imaging for the rheumatologist. XXIV. Sonographic evaluation of wrist and hand joint and tendon involvement in systemic lupus erythematosus. Clin. Exp. Rheumatol. 27, 897–901 (2009).

    CAS  PubMed  Google Scholar 

  9. Wright, S., Filippucci, E., Grassi, W., Grey, A. & Bell, A. Hand arthritis in systemic lupus erythematosus: an ultrasound pictorial essay. Lupus 15, 501–506 (2006).

    Article  CAS  Google Scholar 

  10. Pastershank, S. P. & Resnick, D. “Hook” erosions in Jaccoud's arthropathy. J. Can. Assoc. Radiol. 31, 174–175 (1980).

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Rheumatology, University College London Hospital, 3rd Floor Central, 250 Euston Road, London, NW1 2PQ, UK

    Grainne Murphy

  2. University College London, Centre for Rheumatology, Room 331, Windeyer Building, 46 Cleveland Street, London, W1T 4JF, UK

    David A. Isenberg

Authors
  1. Grainne Murphy
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  2. David A. Isenberg
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Correspondence to David A. Isenberg.

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The authors declare no competing financial interests.

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Murphy, G., Isenberg, D. SLE-associated arthropathy: truly a benign entity?. Nat Rev Rheumatol 8, 695–696 (2012). https://doi.org/10.1038/nrrheum.2012.200

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