Paediatric systemic lupus erythematosus (SLE) has higher morbidity and mortality than adult-onset SLE. Interestingly, a new paper reinforces these differences between adult and childhood disease, but reasons for the more severe phenotype in children are varied and poorly understood.
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Ardoin, S., Schanberg, L. Lessons from SLE: children are not little adults. Nat Rev Rheumatol 8, 444–445 (2012). https://doi.org/10.1038/nrrheum.2012.109
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DOI: https://doi.org/10.1038/nrrheum.2012.109
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