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Regenerative medicine

Self-directed articular resurfacing: a new paradigm?

Tissue engineering to repair diseased or injured cartilage could be revolutionized by the development of a novel cell-homing strategy that overcomes several barriers inherent in the use of existing techniques.

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Figure 1: A cell-homing approach to joint-surface regeneration.

References

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Correspondence to Daniel A. Grande.

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Competing interests

D. A. Grande has acted as a consultant for Arthrocare and TiGenix, and has received grant/research support from and is a stockholder/director of TiGenix. N. Sgaglione has acted as a consultant for Biomet Sports Medicine, ConMed Linvatec and Smith and Nephew Endoscopy, and is a patent holder/applicant for a Biomet Sports Medicine product.

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Grande, D., Sgaglione, N. Self-directed articular resurfacing: a new paradigm?. Nat Rev Rheumatol 6, 677–678 (2010). https://doi.org/10.1038/nrrheum.2010.192

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