Patients with drug-resistant focal epilepsy who lack structural abnormalities on MRI constitute a challenge in presurgical work-up. A longitudinal single-centre study of long-term seizure outcomes in patients with nonlesional epilepsy showed that 59% of the cohort was free from disabling seizures 10 years after resective epilepsy surgery. These results are encouraging and valuable for patient counselling.
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The authors declare no competing financial interests.
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Malmgren, K., Krýsl, D. Long-term outcomes in MRI-negative patients with epilepsy. Nat Rev Neurol 13, 132–133 (2017). https://doi.org/10.1038/nrneurol.2017.24
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