The Lancet Commission on Dementia Prevention, Intervention, and Care has evaluated current evidence on dementia management, including the measures that can be taken to reduce an individual's risk of dementia. However, further intervention trials and evaluation in real-world settings are needed to alter dementia incidence globally.
Subscribe to Journal
Get full journal access for 1 year
only $17.42 per issue
All prices are NET prices.
VAT will be added later in the checkout.
Rent or Buy article
Get time limited or full article access on ReadCube.
All prices are NET prices.
Livingston, G. et al. Dementia prevention, intervention, and care. Lancet http://dx.doi.org/10.1016/S0140-6736(17)31363-6 (2017).
Lafortune, L., Martin, S. & Kelly, S. Midlife approaches to prevention of ill health in later life. JAMA Intern. Med. 177, 423–424 (2017).
Lafortune, L. et al. Changing risk behaviours and promoting cognitive health in older adults: an evidence-based resource for local authorities and commissioners. Public Health England https://goo.gl/SSBTYP (2016).
Matthews, F. E. et al. A two decade dementia incidence comparison from the cognitive function and ageing studies I and II. Nat. Commun. 7, 11398 (2016).
Norton, S. et al. Potential for primary prevention of Alzheimer's disease: an analysis of population-based data. Lancet Neurol. 13, 788–794 (2014).
Wu, Y. T. et al. The changing prevalence and incidence of dementia over time — current evidence. Nat. Rev. Neurol. 13, 327–339 (2017).
National Academies of Sciences, Engineering, and Medicine. Preventing Cognitive Decline and Dementia: a Way Forward (The National Academies Press, 2017).
Rutter, H. et al. The need for a complex systems model of evidence for public health. Lancet http://dx.doi.org/10.1016/S0140-6736(17)31267-9 (2017).
Lafortune, L. et al. Behavioural risk factors in mid-life associated with successful ageing, disability, dementia and frailty in later life: a rapid systematic review. PLoS ONE 11, e0144405 (2016).
Kelly, S. et al. Interventions to prevent and reduce excessive alcohol consumption in older people: a systematic review and meta-analysis. Age Ageing https://doi.org/10.1093/ageing/afx132 (2017).
The authors declare no competing financial interests.
About this article
Cite this article
Lafortune, L., Brayne, C. Dementia prevention — a call for contextualized evidence. Nat Rev Neurol 13, 579–580 (2017). https://doi.org/10.1038/nrneurol.2017.136
MIND food and speed of processing training in older adults with low education, the MINDSpeed Alzheimer's disease prevention pilot trial
Contemporary Clinical Trials (2019)
¿Es posible reducir la prevalencia de demencia? Necesitamos nuevos enfoques para enfrentar la demencia
Medicina de Familia. SEMERGEN (2018)
Nature Reviews Neurology (2017)