Paediatric low-grade gliomas have a good prognosis; however, a recent follow-up study of 1,202 children reports that survivors of childhood low-grade glioma are at increased risk of late mortality. Most of the deaths recorded at follow-up (median 13 years) were linked to tumour transformation or non-oncological causes rather than tumour progression. Radiotherapy was the most important risk factor for late all-cause deaths.