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Multiple sclerosis

Repurposing dopaminergic drugs for MS — the evidence mounts

A new study has shown that both in patients with multiple sclerosis (MS) and in healthy controls, dopamine inhibits production of IL-17 and IFN-γ by peripheral blood mononuclear cells. The finding adds to previous evidence for the potential benefit of dopaminergic drugs in MS.

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Figure 1: IFN-β could alleviate dysfunction of dopaminergic pathways in multiple sclerosis (MS).


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Correspondence to Marco Cosentino.

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Marino, F., Cosentino, M. Repurposing dopaminergic drugs for MS — the evidence mounts. Nat Rev Neurol 12, 191–192 (2016).

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