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Parkinson disease

Could gut microbiota influence severity of Parkinson disease?

Nature Reviews Neurology volume 13, pages 66–67 (2017)Cite this article

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Intestinal microbiota can exacerbate motor deficits in Parkinson disease (PD), according to a mouse study published recently in Cell. “Our findings indicate a role for microbial signals in PD,” says lead author Timothy Sampson from the laboratory of Sarkis Mazmanian at California Institute of Technology, USA.

Our findings indicate a role for microbial signals in PD

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References

  1. Sampson, T. R. et al. Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson's disease. Cell http://dx.doi.org/10.1016/j.cell.2016.11.018 (2016)

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  1. Hemi Malkki
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Klingelhoefer, L. & Reichmann, H. Pathogenesis of Parkinson disease—the gut–brain axis and environmental factors. Nat. Rev. Neurol. 11, 625–636 (2015)

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Malkki, H. Could gut microbiota influence severity of Parkinson disease?. Nat Rev Neurol 13, 66–67 (2017). https://doi.org/10.1038/nrneurol.2016.195

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