A new study has shown that dietary supplementation with a serotonin precursor reduces seizure-induced respiratory arrest (S-IRA) and death in mouse models. Development of strategies to prevent S-IRA is paramount, because S-IRA is thought to be associated with a high risk of sudden unexpected death in epilepsy (SUDEP).
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Change history
12 September 2016
In the version of this article initially published, some of the funding sources were omitted from the Acknowledgements. This error has been corrected in the HTML and PDF versions of the article.
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Acknowledgements
G.F.B. receives support from NINDS/NIH, Epilepsy Foundation, The Beth & Nate Tross Epilepsy Research Fund, and the American Epilepsy Society. G.B.R. receives funding from the NINDS/NIH Center for SUDEP Research (CSR; Center Without Walls).
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Buchanan, G., Richerson, G. A dietary supplement for SUDEP prevention?. Nat Rev Neurol 12, 495–496 (2016). https://doi.org/10.1038/nrneurol.2016.114
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DOI: https://doi.org/10.1038/nrneurol.2016.114
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Erratum: Correction: A dietary supplement for SUDEP prevention?
Nature Reviews Neurology (2016)
