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Multiple sclerosis

Does aggressive MS warrant aggressive treatment?

Aggressive, refractory multiple sclerosis warrants unconventional therapy. A retrospective multicentre study assessed the effects of ablating the immune system, then reconstituting it using bone marrow derived stem cells. Though this particular regimen improved disability in some patients, others continued to relapse, perhaps indicating the treatment did not go far enough.

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Correspondence to Mark S. Freedman.

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The author declares no competing financial interests.

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Freedman, M. Does aggressive MS warrant aggressive treatment?. Nat Rev Neurol 10, 368–370 (2014).

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