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Dementia in 2014

Towards early diagnosis in Alzheimer disease

Improved neuroimaging and molecular markers of Alzheimer disease (AD) have aided diagnosis of AD in the very early stages, and have facilitated differential diagnosis between AD and other neurodegenerative disorders with dementia. The finding that some older individuals can show amyloid-β pathology while remaining cognitively intact raises important questions regarding prevention strategies.

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Figure 1: Factors contributing to AD pathology.

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Correspondence to Agneta Nordberg.

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Nordberg, A. Towards early diagnosis in Alzheimer disease. Nat Rev Neurol 11, 69–70 (2015). https://doi.org/10.1038/nrneurol.2014.257

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  • DOI: https://doi.org/10.1038/nrneurol.2014.257

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