Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.


The worldwide burden of stroke—a blurred photograph


An Addendum to this article was published on 25 March 2014

This article has been updated

Assessing the burden of stroke is essential to improve stroke care. Two recent systematic reviews provide a picture of the worldwide stroke burden. However, poor-quality data sources in low-income and middle-income countries make this a blurred photograph, and set a challenge to expand stroke registries.

Your institute does not have access to this article

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

Change history

  • 25 March 2014

    The correspondence details for this article have changed: the authors wish to update the email address to The details have been amended in the HTML and PDF versions of the article.


  1. Feigin, V. L. et al. Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010. Lancet 383, 245–255 (2014).

    Article  Google Scholar 

  2. Krishnamurthi, R. V. et al. Global and regional burden of first-ever ischaemic and haemorrhagic stroke during 1990–2010: findings from the Global Burden of Disease Study 2010. Lancet Glob. Heal. 1, e259–e281 (2013).

    Article  Google Scholar 

  3. Hankey, G. J. The global and regional burden of stroke. Lancet Glob. Heal. 1, e239–e240 (2013).

    Article  Google Scholar 

  4. Giroud, M., Jacquin, A. & Béjot, Y. The worldwide landscape of stroke in the 21st century. Lancet 383 195–197 (2013).

    Article  Google Scholar 

  5. Von Elm, E. et al. Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting of observational studies. Internist (Berl.) 49, 688–693 (2008).

    CAS  Article  Google Scholar 

  6. Global Burden of Disease Expert Group & Bennett, D. A. Methodology of the global and regional burden of stroke study. Neuroepidemiology 38, 30–40 (2012).

    Article  Google Scholar 

  7. The global burden of disease 2004 update. World Health Organization [online], (2004).

  8. Asplund, K. et al. Multinational comparisons of stroke epidemiology. Evaluation of case ascertainment in the WHO MONICA Stroke Study. World Health Organization monitoring trends and determinants in cardiovascular disease. Stroke 26, 355–360 (1995).

    CAS  Article  Google Scholar 

  9. Truelsen, T. et al. Standard method for developing stroke registers in low-income and middle-income countries: experiences from a feasibility study of a stepwise approach to stroke surveillance (STEPS Stroke). Lancet Neurol. 6, 134–139 (2007).

    CAS  Article  Google Scholar 

  10. SIECV SITS Iberoamerican Stroke register to be implemented in 2009. Safe Implementation of Treatments in Stroke [online], (2009).

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to Exuperio Díez Tejedor.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Fuentes, B., Tejedor, E. The worldwide burden of stroke—a blurred photograph. Nat Rev Neurol 10, 127–128 (2014).

Download citation

  • Published:

  • Issue Date:

  • DOI:

Further reading


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing