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The worldwide burden of stroke—a blurred photograph


An Addendum to this article was published on 25 March 2014

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Assessing the burden of stroke is essential to improve stroke care. Two recent systematic reviews provide a picture of the worldwide stroke burden. However, poor-quality data sources in low-income and middle-income countries make this a blurred photograph, and set a challenge to expand stroke registries.

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  • 25 March 2014

    The correspondence details for this article have changed: the authors wish to update the email address to The details have been amended in the HTML and PDF versions of the article.


  1. Feigin, V. L. et al. Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010. Lancet 383, 245–255 (2014).

    Article  Google Scholar 

  2. Krishnamurthi, R. V. et al. Global and regional burden of first-ever ischaemic and haemorrhagic stroke during 1990–2010: findings from the Global Burden of Disease Study 2010. Lancet Glob. Heal. 1, e259–e281 (2013).

    Article  Google Scholar 

  3. Hankey, G. J. The global and regional burden of stroke. Lancet Glob. Heal. 1, e239–e240 (2013).

    Article  Google Scholar 

  4. Giroud, M., Jacquin, A. & Béjot, Y. The worldwide landscape of stroke in the 21st century. Lancet 383 195–197 (2013).

    Article  Google Scholar 

  5. Von Elm, E. et al. Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting of observational studies. Internist (Berl.) 49, 688–693 (2008).

    Article  CAS  Google Scholar 

  6. Global Burden of Disease Expert Group & Bennett, D. A. Methodology of the global and regional burden of stroke study. Neuroepidemiology 38, 30–40 (2012).

    Article  Google Scholar 

  7. The global burden of disease 2004 update. World Health Organization [online], (2004).

  8. Asplund, K. et al. Multinational comparisons of stroke epidemiology. Evaluation of case ascertainment in the WHO MONICA Stroke Study. World Health Organization monitoring trends and determinants in cardiovascular disease. Stroke 26, 355–360 (1995).

    Article  CAS  Google Scholar 

  9. Truelsen, T. et al. Standard method for developing stroke registers in low-income and middle-income countries: experiences from a feasibility study of a stepwise approach to stroke surveillance (STEPS Stroke). Lancet Neurol. 6, 134–139 (2007).

    Article  CAS  Google Scholar 

  10. SIECV SITS Iberoamerican Stroke register to be implemented in 2009. Safe Implementation of Treatments in Stroke [online], (2009).

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Correspondence to Exuperio Díez Tejedor.

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Fuentes, B., Tejedor, E. The worldwide burden of stroke—a blurred photograph. Nat Rev Neurol 10, 127–128 (2014).

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