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Parkinson disease

Can dopamine transporter imaging define early PD?

Dopaminergic brain imaging might aid early diagnosis of Parkinson disease (PD), but some patients with mild symptoms show no evidence of dopaminergic dysfunction at baseline, and apparently do not progress. Although some of these patients may have been misdiagnosed, others continue to fulfil PD diagnostic criteria despite normal follow-up brain scans.

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R.B. was supported by the Italian National research grant N: RF-2009-153017

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Correspondence to Angelo Antonini.

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Antonini, A., Biundo, R. Can dopamine transporter imaging define early PD?. Nat Rev Neurol 10, 432–433 (2014).

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