Genetic diagnosis of frontotemporal lobar degeneration has become challenging since the identification of a number of autosomal dominantly inherited causative mutations. As highlighted in a new paper, careful characterization of the clinical picture associated with a specific gene defect is mandatory to guide genetic screening, and to establish a diagnostic algorithm for neurology practice.
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Borroni, B., Padovani, A. A new algorithm for molecular diagnostics in FTLD. Nat Rev Neurol 9, 241–242 (2013). https://doi.org/10.1038/nrneurol.2013.72
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DOI: https://doi.org/10.1038/nrneurol.2013.72
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