Genome-wide association studies (GWAS) have uncovered over two dozen candidate Alzheimer disease susceptibility genes; however, the results of these studies showed limited overlap. Two independently performed GWAS involving cohorts from Europe and the US have now identified three additional putative Alzheimer disease genes that show modest but remarkably consistent effects across data sets.
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Bertram, L., Tanzi, R. New light on an old CLU. Nat Rev Neurol 6, 11–13 (2010). https://doi.org/10.1038/nrneurol.2009.213
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DOI: https://doi.org/10.1038/nrneurol.2009.213
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