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Renal metabolism in 2017

Glycolytic adaptation and progression of kidney disease

Nature Reviews Nephrology volume 14, pages 75–76 (2018)Cite this article

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Studies of cellular energetics have revealed important roles of metabolic pathways in determining cell fate and response to injury. Insights from 2017 into the mechanisms underlying these pathways might identify therapeutic targets to minimize injury and promote repair.

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Figure 1: Glycolytic cell metabolism.

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Authors and Affiliations

  1. Department of Internal Medicine, Division of Nephrology, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, Albinusdreef 2, Leiden, 2333 ZA, The Netherlands

    Ton J. Rabelink

  2. Department of Oncology, Laboratory of Angiogenesis and Vascular Metabolism, KU Leuven, Vesalius Research Center, VIB,

    Peter Carmeliet

  3. and the Laboratory of Angiogenesis and Vascular Metabolism, Vesalius Research Center, VIB, Campus Gasthuisberg Herestraat 49, Leuven, 3000, Belgium

    Peter Carmeliet

Authors
  1. Ton J. Rabelink
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  2. Peter Carmeliet
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Correspondence to Ton J. Rabelink.

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The authors declare no competing financial interests.

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Rabelink, T., Carmeliet, P. Glycolytic adaptation and progression of kidney disease. Nat Rev Nephrol 14, 75–76 (2018). https://doi.org/10.1038/nrneph.2017.173

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