Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Haemodialysis

Intradialytic meals: addressing a neglected problem

New data suggest that provision of high-protein, high-calorie intradialytic meals in combination with phosphate binder therapy could be an easy and effective strategy to reduce the risk of malnutrition in patients on haemodialysis. These findings highlight the importance of avoiding excessive dietary restrictions in these patients.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

References

  1. Marcelli, D. et al. Body composition and survival in dialysis patients: results from an international cohort study. Clin. J. Am. Soc. Nephrol. 10, 1192–1200 (2015).

    Article  Google Scholar 

  2. Rhee, C. M. et al. Effect of high-protein meals during hemodialysis combined with lanthanum carbonate in hypoalbuminemic dialysis patients: findings from the FrEDI randomized controlled trial. Nephrol. Dial. Transplant. http://dx.doi.org/10.1093/ndt/gfw323 (2016).

  3. Afsar, B. et al. The relationship between breakfast, lunch and dinner eating pattern and hemodialysis sessions, quality of life, depression and appetite in hemodialysis patients. Int. Urol. Nephrol. 44, 1507–1514 (2012).

    Article  Google Scholar 

  4. Owen, W. F. Jr et al. The urea reduction ratio and serum albumin concentration as predictors of mortality in patients undergoing hemodialysis. N. Engl. J. Med. 329, 1001–1006 (1993).

    Article  Google Scholar 

  5. Iseki, K. et al. Serum albumin is a strong predictor of death in chronic dialysis patients. Kidney Int. 44, 115–119 (1993).

    Article  CAS  Google Scholar 

  6. Dezfuli, A. et al. Severity of hypoalbuminemia predicts response to intradialytic parenteral nutrition in hemodialysis patients. J. Ren. Nutr. 19, 291–297 (2009).

    Article  CAS  Google Scholar 

  7. Sezer, S. et al. Long-term oral nutrition supplementation improves outcomes in malnourished patients with chronic kidney disease on hemodialysis. JPEN J. Parenter. Enteral Nutr. 38, 960–965 (2014).

    Article  Google Scholar 

  8. Beddhu, S. et al. Supervised oral protein supplementation during dialysis in patients with elevated C-reactive protein levels: a two phase, longitudinal, single center, open labeled study. BMC. Nephrol. 16, 87 (2015).

    Article  Google Scholar 

  9. Caglar, K. et al. Therapeutic effects of oral nutritional supplementation during hemodialysis. Kidney Int. 62, 1054–1059 (2002).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Francesco Locatelli.

Ethics declarations

Competing interests

F.L. is a former member of an advisory board for Keryx. L.D.V. declares no competing interests.

PowerPoint slides

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Locatelli, F., Del Vecchio, L. Intradialytic meals: addressing a neglected problem. Nat Rev Nephrol 13, 6–8 (2017). https://doi.org/10.1038/nrneph.2016.172

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrneph.2016.172

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing