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Decade in review—renal transplantation

A spectrum of advances in renal transplantation

Nature Reviews Nephrology volume 11, pages 639–641 (2015)Cite this article

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Although the first 50 years of renal transplantation were marked by great advances in immunosuppressive therapies, the past decade has been marked by an unprecedented increase in technology. This progress has spurred investigators to challenge old paradigms and investigate how best to utilize these technologies to further improve patient care.

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References

  1. Kawai, T. et al. HLA-mismatched renal transplantation without maintenance immunosuppression. N. Engl. J. Med. 358, 353–361 (2008).

    Article  CAS  Google Scholar 

  2. Friedewald, J. J. et al. The kidney allocation system. Surg. Clin. North Am. 93, 1395–1406 (2013).

    Article  Google Scholar 

  3. Einecke, G. et al. A molecular classifier for predicting future graft loss in late kidney transplant biopsies. J Clin. Invest. 120, 1862–1872 (2010).

    Article  CAS  Google Scholar 

  4. Kurian, S. M. et al. Molecular classifiers for acute kidney transplant rejection in peripheral blood by whole genome gene expression profiling. Am. J. Transplant. 14, 1164–1172 (2014).

    Article  CAS  Google Scholar 

  5. Hricik, D. E. et al. Multicenter validation of urinary CXCL9 as a risk-stratifying biomarker for kidney transplant injury. Am. J. Transplant. 13, 2634–2644 (2013).

    Article  CAS  Google Scholar 

  6. Montgomery, R. A. et al. Desensitization in HLA-incompatible kidney recipients and survival. N. Engl. J. Med. 365, 318–326 (2011).

    Article  CAS  Google Scholar 

  7. Rees, M. A. et al. A nonsimultaneous, extended, altruistic-donor chain. N. Engl. J. Med. 360, 1096–1101 (2009).

    Article  CAS  Google Scholar 

  8. Stock, P. G. et al. Outcomes of kidney transplantation in HIV-infected recipients. N. Engl. J. Med. 363, 2004–2014 (2010).

    Article  CAS  Google Scholar 

  9. Vincenti, F. et al. Costimulation blockade with belatacept in renal transplantation. N. Engl. J. Med. 353, 770–781 (2005).

    Article  CAS  Google Scholar 

  10. El-zoghby, Z. M. et al. Identifying specific causes of kidney allograft loss. Am. J. Transplant. 9, 527–535 (2009).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Arizona State University, 550 North 3rd Street, Phoenix, 85004, AZ, USA

    Bruce Kaplan

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  1. Bruce Kaplan
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Correspondence to Bruce Kaplan.

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The author declares no competing financial interests.

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Kaplan, B. A spectrum of advances in renal transplantation. Nat Rev Nephrol 11, 639–641 (2015). https://doi.org/10.1038/nrneph.2015.159

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