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Acute kidney injury in 2014

A step towards understanding mechanisms of renal repair

Nature Reviews Nephrology volume 11, pages 7475 (2015) | Download Citation

In 2014, key articles in the field of acute kidney injury highlighted the importance of tubular homeostasis in renal regeneration. Cell cycle regulators, inflammatory signals and progenitors were identified as important factors that mediate the balance between inflammation and tubular regeneration necessary for renal repair.

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A.B. is supported by a Center for Sepsis and Critical Illness Award P50 GM-111152 from the National Institute of General Medical Sciences.

Author information


  1. Department of Anaesthesiology, University of Florida, 1600 SW Archer Road, Medical Science Building Room M526B, Gainesville, FL 32610, USA.

    • Azra Bihorac
  2. Center for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh, School of Medicine, Room 604 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261, USA.

    • John A. Kellum


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Competing interests

A.B. has received grant support from Astute Medical. J.A.K. has received grant support and consulting fees from Astute Medical and Baxter.

Corresponding author

Correspondence to John A. Kellum.

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