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Risk factors

HDL-cholesterol levels and mortality in patients with ESRD

In the general population, risk of cardiovascular disease is inversely associated with HDL-cholesterol levels. However, a new post hoc analysis of data from the German Diabetes Dialysis study reports no correlation between HDL cholesterol and mortality among patients on dialysis—a phenomenon that the authors attribute to HDL dysfunction.

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Figure 1: Effects of chronic kidney disease on HDL structure and function.


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Correspondence to Nosratola D. Vaziri.

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The author declares no competing financial interests.

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Vaziri, N. HDL-cholesterol levels and mortality in patients with ESRD. Nat Rev Nephrol 10, 621–623 (2014).

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