In 2013, four important papers were published that provide new insights on biomarkers in acute kidney injury (AKI). These studies demonstrate the potential for biomarkers to aid clinicians in improving the therapeutic management of patients with AKI and potentially improve patient outcomes.
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References
Mehta, R. L. Acute kidney injury: urine output in AKI—the canary in the coal mine? Nat. Rev. Nephrol. 9, 568–570 (2013).
Mandelbaum, T. et al. Empirical relationships among oliguria, creatinine, mortality, and renal replacement therapy in the critically ill. Intensive Care Med. 39, 414–419 (2013).
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R. L. Mehta and D. N. Cruz participated in the Acute Dialysis Quality Initiative consensus conference and contributed to drafting the consensus recommendations. D. N. Cruz has received speaking honoraria from Alere and Toray. R. L. Mehta works on clinical research studies with Allocure, Cytopherx, Eli Lilly and Thrasos Therapeutics. He is a consultant for AbbVie, Baxter, CSL Behring, Gambro, GlaxoSmithKline and Grifols. He is an advisor to Astute, the sponsor for the Sapphire study.
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Cruz, D., Mehta, R. Breaking barriers for biomarkers in AKI—progress at last. Nat Rev Nephrol 10, 74–76 (2014). https://doi.org/10.1038/nrneph.2013.268
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DOI: https://doi.org/10.1038/nrneph.2013.268
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