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Podocyte progenitors and ectopic podocytes

Nature Reviews Nephrology volume 9, pages 715–716 (2013)Cite this article

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Two types of parietal podocyte were previously described in the Bowman capsule: one characterized by coexpression of podocyte and parietal epithelial cell markers, the other characterized by expression of podocyte markers only. New research demonstrates that these populations represent podocyte progenitors and ectopic podocytes—distinct cell types with different clinical implications.

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Figure 1: The phenotypes and functions of podocyte progenitors and ectopic podocytes.

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Acknowledgements

P. Romagnani's work is supported by the European Community's Seventh Framework Programme (FP7/2012-2016), grant number 305436.

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Authors and Affiliations

  1. Excellence Centre for Research, Transfer and High Education for the Development of DE NOVO Therapies (DENOTHE), University of Florence, Viale Morgagni 85, Florence, 50134, Italy

    Laura Lasagni

  2. Paediatric Nephrology Unit, Meyer Children's Hospital, University of Florence, Viale Pieraccini 24, Florence, 50139, Italy

    Paola Romagnani

Authors
  1. Laura Lasagni
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  2. Paola Romagnani
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Correspondence to Paola Romagnani.

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The authors declare no competing financial interests.

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Lasagni, L., Romagnani, P. Podocyte progenitors and ectopic podocytes. Nat Rev Nephrol 9, 715–716 (2013). https://doi.org/10.1038/nrneph.2013.247

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