Renal biopsy is the gold standard for detection of rejection in kidney transplant recipients, but is not considered until evidence of renal dysfunction is apparent. Now, Suthanthiran and colleagues suggest that mRNA levels in urinary cells from these patients might be diagnostic and prognostic of acute cellular rejection.
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T. B. Strom has intellectual property on molecular biomarkers for the diagnosis of rejection (US patent #16937).
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Chandraker, A., Strom, T. A new molecular approach to the diagnosis of acute rejection. Nat Rev Nephrol 9, 631–632 (2013). https://doi.org/10.1038/nrneph.2013.199
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DOI: https://doi.org/10.1038/nrneph.2013.199
