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Acute kidney injury

Urine output in AKI—the canary in the coal mine?

Ralib et al. report that urine output (UO) <0.3 ml/kg/h for >6 h predicts a composite outcome of mortality and dialysis requirement in critically ill patients. Their findings validate UO as a marker of acute kidney injury, but raise the question of whether the diagnostic thresholds should be more stringent.

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Mehta, R. Urine output in AKI—the canary in the coal mine?. Nat Rev Nephrol 9, 568–570 (2013). https://doi.org/10.1038/nrneph.2013.178

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