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Acute kidney injury

AKI in acute myocardial infarction—are we making progress?

A recent report suggests that the incidence of acute kidney injury (AKI) in patients with acute myocardial infarction declined between 2000 and 2008 and was associated with decreased mortality despite concurrent increases in comorbidities. Although encouraging, changing patterns of care and an understanding of factors contributing to AKI in this setting must be considered.

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References

  1. Amin, A. P. et al. Trends in the incidence of acute kidney injury in patients hospitalized with acute myocardial infarction. Arch. Intern. Med. 172, 246–253 (2012).

    Article  CAS  Google Scholar 

  2. Chawla, L. S., Amdur, R. L., Amodeo, S., Kimmel, P. L. & Palant, C. E. The severity of acute kidney injury predicts progression to chronic kidney disease. Kidney Int. 79, 1361–1369 (2011).

    Article  Google Scholar 

  3. Hsu, C. Y. et al. Community-based incidence of acute renal failure. Kidney Int. 72, 208–212 (2007).

    Article  Google Scholar 

  4. Waikar, S. S. et al. Validity of International Classification of Diseases, Ninth Revision, Clinical Modification Codes for Acute Renal Failure. J. Am. Soc. Nephrol. 17, 1688–1694 (2006).

    Article  Google Scholar 

  5. Mehta, R. L. et al. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit. Care 11, R31 (2007).

    Article  Google Scholar 

  6. Ricci, Z., Cruz, D. N. & Ronco, C. Classification and staging of acute kidney injury: beyond the RIFLE and AKIN criteria. Nat. Rev. Nephrol. 7, 201–208 (2011).

    Article  CAS  Google Scholar 

  7. Wang, O. J., Wang, Y., Chen, J. & Krumholz, H. M. Recent trends in hospitalization for acute myocardial infarction. Am. J. Cardiol. http://dx.doi.org/10.1016/j.amjcard.2012.01.381.

  8. Chen, J. et al. Recent declines in hospitalizations for acute myocardial infarction for Medicare fee-for-service beneficiaries: progress and continuing challenges. Circulation 121, 1322–1328 (2010).

    Article  Google Scholar 

  9. Waikar, S. S., Curhan, G. C., Ayanian, J. Z. & Chertow, G. M. Race and mortality after acute renal failure. J. Am. Soc. Nephrol. 18, 2740–2748 (2007).

    Article  Google Scholar 

  10. Abraham, K. A., Thompson, E. B., Bodger, K. & Pearson, M. Inequalities in outcomes of acute kidney injury in England. QJM http://dx.doi.org/10.1093/qjmed/hcs037.

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Mehta, R. AKI in acute myocardial infarction—are we making progress?. Nat Rev Nephrol 8, 322–323 (2012). https://doi.org/10.1038/nrneph.2012.80

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