Acute kidney injury

AKI in acute myocardial infarction—are we making progress?

A recent report suggests that the incidence of acute kidney injury (AKI) in patients with acute myocardial infarction declined between 2000 and 2008 and was associated with decreased mortality despite concurrent increases in comorbidities. Although encouraging, changing patterns of care and an understanding of factors contributing to AKI in this setting must be considered.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Amin, A. P. et al. Trends in the incidence of acute kidney injury in patients hospitalized with acute myocardial infarction. Arch. Intern. Med. 172, 246–253 (2012).

  2. 2

    Chawla, L. S., Amdur, R. L., Amodeo, S., Kimmel, P. L. & Palant, C. E. The severity of acute kidney injury predicts progression to chronic kidney disease. Kidney Int. 79, 1361–1369 (2011).

  3. 3

    Hsu, C. Y. et al. Community-based incidence of acute renal failure. Kidney Int. 72, 208–212 (2007).

  4. 4

    Waikar, S. S. et al. Validity of International Classification of Diseases, Ninth Revision, Clinical Modification Codes for Acute Renal Failure. J. Am. Soc. Nephrol. 17, 1688–1694 (2006).

  5. 5

    Mehta, R. L. et al. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit. Care 11, R31 (2007).

  6. 6

    Ricci, Z., Cruz, D. N. & Ronco, C. Classification and staging of acute kidney injury: beyond the RIFLE and AKIN criteria. Nat. Rev. Nephrol. 7, 201–208 (2011).

  7. 7

    Wang, O. J., Wang, Y., Chen, J. & Krumholz, H. M. Recent trends in hospitalization for acute myocardial infarction. Am. J. Cardiol.

  8. 8

    Chen, J. et al. Recent declines in hospitalizations for acute myocardial infarction for Medicare fee-for-service beneficiaries: progress and continuing challenges. Circulation 121, 1322–1328 (2010).

  9. 9

    Waikar, S. S., Curhan, G. C., Ayanian, J. Z. & Chertow, G. M. Race and mortality after acute renal failure. J. Am. Soc. Nephrol. 18, 2740–2748 (2007).

  10. 10

    Abraham, K. A., Thompson, E. B., Bodger, K. & Pearson, M. Inequalities in outcomes of acute kidney injury in England. QJM

Download references

Author information

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Mehta, R. AKI in acute myocardial infarction—are we making progress?. Nat Rev Nephrol 8, 322–323 (2012).

Download citation