Two trials recently reported in the New England Journal of Medicine report that use of mammalian target of rapamycin inhibitors does little to halt the progression of autosomal dominant polycystic kidney disease. Do these therapies still have a future in the treatment of this disease?
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References
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Acknowledgements
N. Perico and G. Remuzzi are both authors on reference 9; G. Remuzzi is also an author on reference 10.
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Perico, N., Remuzzi, G. Do mTOR inhibitors still have a future in ADPKD?. Nat Rev Nephrol 6, 696–698 (2010). https://doi.org/10.1038/nrneph.2010.153
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DOI: https://doi.org/10.1038/nrneph.2010.153
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