Acute kidney injury

Defining prerenal azotemia in clinical practice and research

Prerenal azotemia is a common occurrence in hospitalized patients and is generally easier to define in clinical practice than in clinical research. Monitoring the duration of acute kidney injury and biomarkers of kidney function might help distinguish prerenal azotemia from acute tubular necrosis in both clinical practice and research settings.

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Figure 1: Classification systems for AKI.


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C. R. Parikh was supported by NIH grants UO1- DK82185 and RO1-HL85757. S. G. Coca was supported by the career development grant K23DK08013 from the NIH.

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Correspondence to Chirag R. Parikh.

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The authors declare no competing financial interests.

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Parikh, C., Coca, S. Defining prerenal azotemia in clinical practice and research. Nat Rev Nephrol 6, 641–642 (2010).

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