Masked hypertension—which is present in about 25% of adult patients initially classified as normotensive—is associated with left ventricular hypertrophy and is a well-documented marker of cardiovascular risk in adults. A recent study has found that masked hypertension is also an important and underdiagnosed cardiovascular risk factor in children.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Mitsnefes, M. M. et al. Masked hypertension associates with left ventricular hypertrophy in children with CKD. J. Am. Soc. Nephrol. doi: 10.1681/ASN.2009060609.
Khattar, R. S., Senior, R. & Lahiri, A. Cardiovascular outcome in white-coat versus sustained mild hypertension: a 10-year follow-up study. Circulation 98, 1892–1897 (1998).
Liu, E. et al. Cardiac and arterial target organ damage in adults with elevated ambulatory and normal office blood pressure. Ann. Intern. Med. 131, 564–572 (1999).
Sega, R. et al. Alterations of cardiac structure in patients with isolated office, ambulatory, or home hypertension: data from the general population (Presione Arteriose Monitorate E Loro Association [PAMELA] Study). Circulation 104, 1385–1392 (2001).
Lurbe, E. et al. Prevalence, persistence and clinical significance of masked hypertension in youth. Hypertension 45, 493–498 (2005).
Pogue, V. et al. Disparate estimates of hypertension control from ambulatory and clinic blood pressure measurements in hypertensive kidney disease. Hypertension 53, 20–27 (2009).
Clement, D. L. et al. Prognostic value of ambulatory blood pressure recordings in patients with treated hypertension. N. Engl. J. Med. 348, 2407–2415 (2003).
Sim, J. J. et al. Sleep apnea in early and advanced chronic kidney disease: Kaiser Permanente Southern California Cohort. Chest 135, 710–716 (2009).
Kario, K. Obstructive sleep apnea syndrome and hypertension: metabolism of the linkage and 24 hr blood pressure control. Hypertens. Res. 32, 537–541 (2009).
Sim, J. J. Rasgon, S. A. & Derose, S. F. Sleep apnea and hypertension: prevalence in chronic kidney disease. J. Clin. Hypertens. (Greenwich) 9, 837–841 (2007).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Mak, R., Bakris, G. Masked hypertension: a risk factor in children with CKD. Nat Rev Nephrol 6, 132–134 (2010). https://doi.org/10.1038/nrneph.2010.12
Issue Date:
DOI: https://doi.org/10.1038/nrneph.2010.12
This article is cited by
-
Blood pressure variability is independent of systolic pressure in adolescent and young adult patients undergoing hemodialysis
Pediatric Research (2018)
-
Using a dual kernel density estimate as a preliminary evaluation of the spatial distribution of diagnosed chronic kidney disease (CKD) in Edo State, Nigeria
GeoJournal (2015)
