Although events occurring over short timescales and distances are represented in the hippocampus, whether the longer times and distances are also represented is not known. Human participants who were asked to recall events from the previous month while undergoing functional MRI exhibited neural activity patterns in the left anterior hippocampus that differed according to the spatial or temporal proximity of the original experiences. Furthermore, the spatial distance and temporal distance between memories were significantly correlated with neural distance in the left anterior hippocampus, suggesting a specific spatiotemporal organization of memories that are separated in space and time.
Nielson, D. M. et al. Human hippocampus represents space and time during retrieval of real-world memories. Proc. Natl Acad. Sci. USA 112, 11078–11083 (2015)
Rights and permissions
About this article
Cite this article
Lewis, S. Remembering in space and time. Nat Rev Neurosci 16, 578 (2015). https://doi.org/10.1038/nrn4033