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Memory

Scaffolding fearful thoughts

Nature Reviews Neuroscience volume 9, pages 804–805 (2008)Cite this article

In the amygdala of wild-type mice, the authors found a significant increase in the levels of β-catenin mRNA and phosphorylated β-catenin 2 hours after fear conditioning. In particular, Tyr654-phosphorylated β-catenin, which has decreased affinity for the β-catenin binding partner cadherin, was increased, suggesting that this interaction is dynamically regulated during fear consolidation.

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ORIGINAL RESEARCH PAPER

  1. Maguschak, K. A. & Ressler, K. J. β-Catenin is required for memory consolidation. Nature Neurosci. 28 Sep 2008 (doi:10.1038/nn.2198)

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  1. Monica Hoyos Flight
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Flight, M. Scaffolding fearful thoughts. Nat Rev Neurosci 9, 804–805 (2008). https://doi.org/10.1038/nrn2524

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