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How widespread is adult neurogenesis in mammals?

Nature Reviews Neuroscience volume 8, pages 481488 (2007) | Download Citation

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Abstract

It is now widely accepted that neurogenesis occurs in two regions of the adult mammalian brain — the hippocampus and the olfactory bulb. There is evidence for adult neurogenesis in several additional areas, including the neocortex, striatum, amygdala and substantia nigra, but this has been difficult to replicate consistently other than in the damaged brain. The discrepancies may be due to variations in the sensitivity of the methods used to detect new neurons.

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Acknowledgements

The author thanks C. Gross, B. Leuner, Y. Kozorovitskiy and E. Glasper for helpful comments on the manuscript.

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  1. Elizabeth Gould is at the Department of Psychology, Princeton University, Princeton, New Jersey 08544, USA.  goulde@princeton.edu

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The author declares no competing financial interests.

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https://doi.org/10.1038/nrn2147