Sunrise and sunset in fly brains. Schwartz, W. J. Nature 14 October (2004) This News and Views article underscores the importance of networks of cells in controlling the circadian rhythms in fruitflies.

Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases. Selkoe, D. J. Nature Cell Biology November (2004)

Gangliosides help stabilize the brain. Proia, R. L. Nature Genetics November (2004) Lysosomal storage diseases are caused by interference with the breakdown of gangliosides, which are glycolipids that are found in abundance in the brain. New work showing that abnormalities in the synthesis of gangliosides are responsible for an inherited form of epilepsy is described in this News and Views article.

Lifespan and mitochondrial control of neurodegeneration. Wright, A. F. et al. Nature Genetics November (2004)

Nucleokinesis illuminated. Samuels, B. A. & Tsai, L.-H. Nature Neuroscience November (2004) This News and Views piece describes a study that used live imaging to show the cytoskeletal structures and regulating proteins that are involved in the migration of newborn cerebellar neurons along radial glial processes.

Festina lente: late-night thoughts on high-throughput screening of mouse behavior. Crabbe, J. C. & Morris, R. G. M. Nature Neuroscience November (2004)

Messing about in memory. Morris, R. G. M. & Rugg, M. D. Nature Neuroscience November (2004)

Decision making, performance and outcome monitoring in frontal cortical areas. Ullsperger, M. & von Cramon, D. Y. Nature Neuroscience November (2004)

Emotional vision. Adolphs, R. Nature Neuroscience November (2004) New work that combined imaging and patient data to determine the region of the brain that supports the modulation of perception by emotion is discussed in this News and Views article.

A brain in the hand. Aleksander, I. Nature 4 November (2004) A review of the book On Intelligence: How a New Understanding of the Brain Will Lead to the Creation of Truly Intelligent Machines by J. Hawkins with S. Blakeslee.

Insight: plasticity and neuronal computation.Nature 14 October (2004) A collection of Review articles that highlight plasticity as a fundamental source of computational power in the brain, from the perspectives of bench neuroscientists through to computational neuroscientists.

Computational roles for dopamine in behavioural control. Montague, P. R., Hyman, S. E. & Cohen, J. D.

Neural networks and perceptual learning. Tsodyks, M. & Gilbert, C.

Plasticity in single neuron and circuit computations. Destexhe, A. & Marder, E.