Abstract
Long-term potentiation has captured the attention of neuroscientists for over two decades. It has provided motivation to investigate the detailed mechanisms of synaptic transmission and remains a prime candidate for mediating circuit modifications during development and experience-dependent plasticity. However, much remains to be learned about this fascinating phenomenon, which will certainly continue to entice neuroscientists throughout the twenty-first century.
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Acknowledgements
I thank J. Kauer, R. Nicoll and members of my laboratory for helpful discussion and comments.
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Malenka, R. The long-term potential of LTP. Nat Rev Neurosci 4, 923–926 (2003). https://doi.org/10.1038/nrn1258
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DOI: https://doi.org/10.1038/nrn1258
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