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Decision making

Valuable choices

In value-based decision making, it has been suggested that the complex feature spaces of different goods are reduced to single values that allow comparisons (economic choice) to be made in the context of current circumstances and wants (model-based behaviour). Optogenetically inactivating the rat lateral orbitofrontal cortex during an economic choice task had no effect on economic choice but affected model-based behaviour when a rat's 'wants' were manipulated, indicating that these behaviours are dissociable.


  1. Gardner, M. P. et al. Lateral orbitofrontal inactivation dissociates devaluation-sensitive behavior and economic choice. Neuron (2017)

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Lewis, S. Valuable choices. Nat Rev Neurosci 19, 3 (2018).

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